| ncRNA name | H-Ras siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Bos taurus |
| Tissues/Cell_line | bovine retinal endothelial cells |
| Methods | siRNA transfection, zymography, qPCR, Western blot, ELISA |
| Expression pattern | associated |
| Functional description | Inhibition of H-Ras, both in diabetic rats (simvastatin) and in isolated endothelial cells (H-Ras siRNA), abrogated the activation of MMP-9 and prevented the reduction of TIMP-1. |
| PubMed ID | 20220057 |
| Year | 2010 |
| Title | Role of matrix metalloproteinase-9 in the development of diabetic retinopathy and its regulation by H-Ras. |
| Drug-related ncRNA | NO |
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